| Description | N-(3-Aminopropyl)cyclohexylamine, a derivative of cyclohexylamine, functions as a selective and competitive inhibitor of spermine synthase, making it suitable for research on neurological diseases[1]. |
| In vitro | N-(3-Aminopropyl)cyclohexylamine在浓度高达10(-6)M时，不影响神经元的存活，但显著阻断了精胺(10(-8)M)对神经元存活促进作用[1]。同样，APCHA也阻断了精胺诱导的轴突切断后神经突起再生的促进作用[1]。在原代培养的大脑神经元中，APCHA主要作为精胺对立剂，而非精胺合成抑制剂[1]。 |
| molecular weight | 156.2685 |
| Molecular formula | C9H20N2 |
| CAS | 3312-60-5 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | H2O: 95 mg/mL (607.92 mM), Sonication is recommended. |
| References | 1. P J Chu, et al. Antagonistic effect of N-(3-Aminopropyl)cyclohexylamine on neurotrophic action of spermine in primary cultured rat hippocampal and cerebellar neurons. Jpn J Pharmacol. 1995 Dec;69(4):311-5. |
N-(3-Aminopropyl)cyclohexylamine
CAS No.: 3312-60-5
N-(3-Aminopropyl)cyclohexylamine, a derivative of cyclohexylamine, functions as a selective and competitive inhibitor of
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