| Description | MY-673, a colchicine binding site inhibitor (CBSI), impedes tubulin polymerization and disrupts the ERK signaling pathway, consequently modulating SMAD4 protein expression in the TGF-β/SMAD pathway. This compound effectively reduces cell proliferation and migration while inducing apoptosis in both in vivo and in vitro settings [1]. |
| molecular weight | 322.31 |
| Molecular formula | C18H14N2O4 |
| CAS | 2944459-96-3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |