PeptideDB

MuRF1-IN-1

CAS No.: 445222-91-3

MuRF1-IN-1 is an inhibitor of muscle ring finger 1.
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Description MuRF1-IN-1 is an inhibitor of muscle ring finger 1.
In vitro MuRF1-IN-1能有效抑制MuRF1与titin的复合,IC50值低于25 μM。
molecular weight 321.33
Molecular formula C18H15N3O3
CAS 445222-91-3
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility DMSO: 60 mg/ml (186.72 mM)
References 1. Bowen TS, Adams V, Werner S, et al. Small-molecule inhibition of MuRF1 attenuates skeletal muscle atrophy and dysfunction in cardiac cachexia. J Cachexia Sarcopenia Muscle. 2017 Dec;8(6):939-953.