| Description | Mulberrin (Kuwanon C) is an inhibitor of OATP2B1-mediated estrone-3-sulfate (E3S) uptake (IC50: 1.8 ±1.5 μM). |
| In vitro | Mulberrin是一种强效的OATP2B1抑制剂，抑制率超过80%。同时，Mulberrin也能抑制有机阴离子转运肽(OATP)介导的Fluvastatin、Atorvastatin和Rosuvastatin的摄取。 |
| Synonyms | 桑黄酮, Kuwanon C |
| molecular weight | 422.47 |
| Molecular formula | C25H26O6 |
| CAS | 62949-79-5 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 65 mg/mL (153.86 mM) |
| References | 1. Wen F, et al. Identification of natural products as modulators of OATP2B1 using LC-MS/MS to quantify OATP-mediated uptake. Pharm Biol. 2016;54(2):293-302. |