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mTOR kinase Inhibitor 2

CAS No.: 1021917-65-6

2H-Imidazo[4,5-b]pyrazin-2-one, 1,3-dihydro-6-[6-(1-hydroxy-1-​methylethyl)-3-pyridinyl]-1-[(tetrahydro-2H-pyran-4-yl)m
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Description 2H-Imidazo[4,5-b]pyrazin-2-one, 1,3-dihydro-6-[6-(1-hydroxy-1-​methylethyl)-3-pyridinyl]-1-[(tetrahydro-2H-pyran-4-yl)methyl]- is a potent mTOR inhibitor with IC50 of 0.176 μM and >30 μM for mTOR and PI3Kα, respectively.
molecular weight 369.42
Molecular formula C19H23N5O3
CAS 1021917-65-6
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility DMSO: 50 mg/mL (135.35 mM)