| Description | Mt KARI-IN-2 (compound 5b) is a highly effective inhibitor of Mycobacterium tuberculosis ketol-acid reductoisomerase (Mtb KARI), with a Ki value of 2.02 μM. This compound also exhibits inhibitory activity against Mtb H37Rv, with a MIC value of 0.78 μM. Moreover, Mt KARI-IN-2 demonstrates low cytotoxicity, as evidenced by a HEK IC 50 greater than 86 μg/mL [1]. |
| molecular weight | 377.4 |
| Molecular formula | C14H11N5O4S2 |
| CAS | 2413974-52-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |