| Description | Msr-Ratio (Msr-green) (Msr-green) is a ratiometric fluorescent probe specifically designed for the detection of methionine sulfoxide reductase (MSR) activity. It has an excitation wavelength of 375 nm and an emission wavelength of 550 nm. This probe offers the ability to monitor the enzyme activity both in vitro and in live cells, making it a valuable tool for studying MSR function. |
| In vitro | Msr-Ratio通过蛋氨酸亚砜还原酶转化为其相应的硫化物形式。Msr-Ratio展现出诸多优异性质，包括近400倍的荧光变化、快速的响应率（<30分钟）、大的斯托克斯位移（120nM）以及绿色发射（550nM）[1]。在活体HL60细胞中加入Msr-Ratio后，背景信号极弱。随着Msr-Ratio（10μM）在细胞中的孵育时间从0增加到8小时，荧光信号持续增强[1]。 |
| Synonyms | Msr-green, Msr-Ratio |
| molecular weight | 310.37 |
| Molecular formula | C18H14O3S |
| CAS | 2290635-22-0 |
| Storage | keep away from direct sunlight|Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 3.1 mg/mL (10 mM) |
| References | 1. Liangwei Zhang, et al. A ratiometric fluorescent probe of methionine sulfoxide reductase with an improved response rate and emission wavelength. Chem Commun (Camb). 2019 Jan 29;55(10):1502-1505. |