| Description | MQAE, a fluorescent chloride ion indicator, is more sensitive and selective than 36Cl and microelectrode-based methods for chloride measurement in cells. MQAE is quenched via collision with chloride. |
| In vitro | 当在急性脑切片中浴液应用时，MQAE能够高质量标记神经细胞及其过程[1]。MQAE的荧光是一种适宜且可比较的方法，用于测量数十个单独细胞中的cAMP依赖性氯离子转运[2]。MQAE还可用于测量大鼠主动脉平滑肌细胞（VSMC）原代培养中的细胞内氯离子浓度[3]。 |
| molecular weight | 326.19 |
| Molecular formula | C14H16BrNO3 |
| CAS | 162558-52-3 |
| Storage | store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 55 mg/mL (168.61 mM) |
| References | 1. Kovalchuk Y, et al. Two-photon chloride imaging using MQAE in vitro and in vivo. Cold Spring Harb Protoc. 2012 Jul 1;2012(7):778-85. 2. Andersson C, et al. Determination of chloride efflux by X-ray microanalysis versus MQAE-fluorescence. Microsc Res Tech. 2002 Dec 15;59(6):531-5. 3. Koncz C, et al. Use of MQAE for measurement of intracellular [Cl-] in cultured aortic smooth muscle cells. Am J Physiol. 1994 Dec;267(6 Pt 2):H2114-23. |