| Description | Morniflumate (Niflam) is a nonsteroidal anti-inflammatory drug. It is used to treat inflammation. |
| Synonyms | 马尼氟酯, Niflam, UP 164, UP-164, Morniflu, UP164 |
| molecular weight | 395.38 |
| Molecular formula | C19H20F3N3O3 |
| CAS | 65847-85-0 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 60 mg/ml (151.75 mM) |
| References | 1. Cremonesi G, Cavalieri L. Efficacy and safety of morniflumate for the treatment of symptoms associated with soft tissue inflammation. J Int Med Res. 2015 Jun;43(3):290-302. doi: 10.1177/0300060514567212. Epub 2015 Apr 28. Review. PubMed PMID: 25921871. 2. Cho HY, Park GK, Lee YB. Simultaneous determination of morniflumate and its major active metabolite, niflumic acid, in human plasma by high-performance liquid chromatography in stability and pharmacokinetic studies. Biomed Chromatogr. 2013 Nov;27(11):1438-43. doi: 10.1002/bmc.2940. Epub 2013 May 30. PubMed PMID: 23722315. 3. Mero F, Nettis E, Aloia AM, Di Leo E, Ferrannini A, Vacca A. Short-term tolerability of morniflumate in patients with cutaneous hypersensitivity reactions to non-steroidal anti-inflammatory drugs. Int J Immunopathol Pharmacol. 2013 Jan-Mar;26(1):247-50. PubMed PMID: 23527729. 4. Civelli M, Vigano T, Acerbi D, Caruso P, Giossi M, Bongrani S, Folco GC. Modulation of arachidonic acid metabolism by orally administered morniflumate in man. Agents Actions. 1991 Jul;33(3-4):233-9. PubMed PMID: 1659152. |