| Description | Myelin Oligodendrocyte Glycoprotein (MOG) peptide (35-55) , mouse, rat acetate is a MOG peptide (35-55) derivative. MOG peptide (35-55) is a part of myelin oligodendrocyte glycoprotein (MOG) immunogenic peptide and can be used to study immune-related diseases. |
| In vitro | 小鼠和大鼠的髓鞘少突胶质细胞糖蛋白肽(MOG (35-55))在0至50 μg/mL的浓度范围内作用72小时，可诱导T细胞增殖并触发Th1型细胞因子的分泌，包括TNF-α、IL-10、IFN-γ、IL-4和IL-5。此外，它还增强了IgG的产生。[1] |
| In vivo | 髓鞘少突胶质细胞糖蛋白肽(35-55)，小鼠，MOG peptide (35-55) , mouse, rat acetate（200 μg（0.2 mL）；腹腔内；一次性，持续38天）在HLA-DR2 (DRB1*1501) 小鼠中显示出脑炎特性[1]。 |
| Synonyms | Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat acetate, MOG peptide (35-55) , mouse, rat acetate (149635-73-4 Free base) |
| molecular weight | N/A |
| Storage | store at low temperature,keep away from moisture|Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | H2O: 90.0 mg/mL (34.1 mM), Sonication is recommended. |
| References | 1. Rich C, et al. Myelin oligodendrocyte glycoprotein-35-55 peptide induces severe chronic experimental autoimmune encephalomyelitis in HLA-DR2-transgenic mice. Eur J Immunol. 2004;34(5):1251-1261. 2. Slavin A, et al. Induction of a multiple sclerosis-like disease in mice with an immunodominant epitope of myelin oligodendrocyte glycoprotein. Autoimmunity. 1998;28(2):109-120. 3. Giralt M, et al. Active Induction of Experimental Autoimmune Encephalomyelitis (EAE) with MOG35-55 in the Mouse. Methods Mol Biol. 2018;1791:227-232. |