| Description | Modotuximab (Anti-Human EGFR Recombinant Antibody), an IgG1κ-type chimeric antibody, selectively binds to human EGFR protein. Incorporating elements from Futuximab, it targets two distinct, non-overlapping epitopes on EGFR, facilitating receptor cross-linking, subsequent cellular internalization, and degradation. This action confers Modotuximab's antitumor activity in vivo [1]. |
| Synonyms | Sym 004, DS 1024 |
| molecular weight | N/A |
| CAS | 1310460-86-6 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 years | Shipping with blue ice. |