| Description | MNI 137 is a negative allosteric modulator of mGlu2. MNI 137 inhibits glutamate-induced calcium mobilization with IC50s of 8.3 and 12.6 nM for human and rat. |
| molecular weight | 341.16 |
| Molecular formula | C15H9BrN4O |
| CAS | 946619-21-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 17.06 mg/mL (45.0 mM) |
| References | 1. Hemstapat K, et al. A novel family of potent negative allosteric modulators of group II metabotropic glutamate receptors. J Pharmacol Exp Ther. 2007;322(1):254-264. |