| Description | MMP-9-IN-1 is an inhibitor of specific matrix metalloproteinase-9 (MMP-9). |
| In vitro | MMP-9-IN-1 通过减少细胞迁移和增殖，抑制肿瘤生长和转移。 |
| Cell experiments | Cell Line:HT-1080 and MDA-MB-435 cancer cells expressing endogenous MMP-9. Concentration:10 μM.Incubation Time:9 days |
| molecular weight | 369.39 |
| Molecular formula | C16H17F2N3O3S |
| CAS | 502887-71-0 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 125 mg/mL (338.40 mM), Sonication is recommended. |
| References | 1. Dufour A, et al. Small-molecule anticancer compounds selectively target the hemopexin domain of matrix metalloproteinase-9. Cancer Res. 2011 Jul 15;71(14):4977-88. |
| Citations | 1. Shuyuan F, Yan F X, Kun L, et al.Transcriptomics‐based study of the protective effect of ethyl gallate on intestinal ischemia‐reperfusion injury in mice.Chemistry & Biodiversity.2022 |