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MLN-3897 TFA

CAS No.:

MLN-3897 TFA is a potent CCR1 antagonist that inhibits the binding of 125I-MIP-1α to THP-1 cell membranes.
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Description MLN-3897 TFA is a potent CCR1 antagonist that inhibits the binding of 125I-MIP-1α to THP-1 cell membranes.
Synonyms MLN-3897 TFA(1010731-97-1 Free base)
molecular weight 633.05
Molecular formula C32H32ClF3N2O6
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility DMSO: 6.33 mg/mL (10 mM)
References 1. Gilchrist A, et al. Identifying bias in CCR1 antagonists using radiolabelled binding, receptor internalization, β-arrestin translocation and chemotaxis assays. Br J Pharmacol. 2014 Nov;171(22):5127-38.