| Description | ML-211 is a carbamate-based dual inhibitor of LYPLA1 (IC50 = 17 nM) and the related LYPLA2 (IC50 = 30 nM) |
| Target activity | LYPLA2:30 nM, LYPLA1:17 nM |
| molecular weight | 418.53 |
| Molecular formula | C25H30N4O2 |
| CAS | 2205032-89-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 4.18 mg/mL (10 mM) |
| References | 1. Adibekian A , Martin B R , Chang J W , et al. Characterization of a Selective, Reversible Inhibitor of Lysophospholipase 2 (LYPLA2)[J]. National Center for Biotechnology Information (US), 2010. 2. Adibekian A , Hsu K L , Speers A E , et al. Optimization and characterization of a triazole urea inhibitor for alpha/beta hydrolase domain-containing protein 11 (ABHD11): anti-probe for LYPLA1/LYPLA2 dual inhibitor ML211[M]. PubMed, 2010. |