| Description | ML-095 hydrochloride (CID-25067483 hydrochloride) is a specific placental alkaline phosphatase inhibitor. It inhibits PLAP, TNAP and IAP with IC50 of 2.1, >100 and 53 μM, respectively. |
| Target activity | PLAP:2.1 μM, IAP:53 μM, TNAP:>100 μM |
| Synonyms | CID-25067483 hydrochloride, MLS-0315848 hydrochloride |
| molecular weight | 282.72 |
| Molecular formula | C13H15ClN2O3 |
| CAS | 1135318-57-8 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 4 mg/mL (14.15 mM) |
| References | 1. Sergienko E , Garcia X , Brown B , et al. Placental Alkaline Phosphatase (PLAP) Luminescent HTS assay - Probe 2[M]// Probe Reports from the NIH Molecular Libraries Program. PubMed, 2010. |