| Description | MK-6240 is a tau positron emission tomography (PET) tracer for neurofibrillary tangles (NFTs). MK-6240 exhibits high specificity and selectivity for binding to NFTs. |
| molecular weight | 278.28 |
| Molecular formula | C16H11FN4 |
| CAS | 1841078-87-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 12.5 mg/mL (44.92 mM), Sonication is recommended. |
| References | 1. Walji AM, et al. Discovery of 6-(Fluoro-(18)F)-3- (1H-pyrrolo [2,3-c]pyridin-1-yl) isoquinolin-5-amine ([(18)F]-MK-6240): A Positron Emission Tomography (PET) Imaging Agent for Quantification of Neurofibrillary Tangles (NFTs). J Med Chem. 2016 May 26;59(10):4778-89. |