| Description | MK 0852 is the platelet GP IIb/IIIa cyclic heptapeptide antagonist. |
| Synonyms | MK-0852, L-367,073, MK0852, L 367,073, L367,073 |
| molecular weight | 869.98 |
| Molecular formula | C34H47N9O12S3 |
| CAS | 138199-64-1 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Zhao L, Bath P, Lösche W, Heptinstall S. Platelet-monocyte interaction and GPIIb/IIIa blockade. Thromb Haemost. 2004 Oct;92(4):888-90. PubMed PMID: 15467921. 2. Zhao L, Bath PM, May J, Lösche W, Heptinstall S. P-selectin, tissue factor and CD40 ligand expression on platelet-leucocyte conjugates in the presence of a GPIIb/IIIa antagonist. Platelets. 2003 Nov-Dec;14(7-8):473-80. Erratum in: Platelets. 2004 Feb;15(1):63. PubMed PMID: 14713516. 3. Zhao L, Bath PM, Fox S, May J, Judge H, Lösche W, Heptinstall S. The effects of GPIIb-IIIa antagonists and a combination of three other antiplatelet agents on platelet-leukocyte interactions. Curr Med Res Opin. 2003;19(3):178-86. PubMed PMID: 12803731. 4. Lages B, Weiss HJ. Greater inhibition of platelet procoagulant activity by antibody-derived glycoprotein IIb--IIIa inhibitors than by peptide and peptidomimetic inhibitors. Br J Haematol. 2001 Apr;113(1):65-71. PubMed PMID: 11328283. |