| Description | Mitiglinide calcium hydrate (S-21403 calcium hydrate) is a drug for the treatment of type 2 diabetes. Mitiglinide is thought to stimulate insulin secretion by closing the ATP-sensitive K(+) K(ATP) channels in pancreatic beta-cells. Mitiglinide belongs to the meglitinide class of blood glucose-lowering drugs and is currently co-marketed in Japan by Kissei and Takeda. |
| Synonyms | KAD-1229 calcium hydrate, 米格列奈钙, Mitiglinide calcium, S-21403 calcium hydrate |
| molecular weight | 704.91 |
| Molecular formula | C38H52CaN2O8 |
| CAS | 207844-01-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 25 mg/mL (35.47 mM) |
| References | 1. Malaisse WJ. Expert Opin PharmacOthers. 2008 Oct;9(15):2691-8. |