| Description | Micrococcin P1 is a macrocyclic peptide antibiotic and is a potent hepatitis C virus (HCV) inhibitor(EC50 range of 0.1-0.5 μM) |
| Synonyms | 微球菌素 P1 |
| molecular weight | 1144.36 |
| Molecular formula | C48H49N13O9S6 |
| CAS | 67401-56-3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Lee M, et al. Micrococcin P1, a naturally occurring macrocyclic peptide inhibiting hepatitis C virus entry in a pan-genotypic manner. Antiviral Res. 2016 Aug;132:287-95. 2. Akasapu S, et al. Total synthesis of micrococcin P1 and thiocillin I enabled by Mo(vi) catalyst. Chem Sci. 2018 Dec 3;10(7):1971-1975. 3. Carnio MC, et al. Pyridinyl polythiazole class peptide antibiotic micrococcin P1, secreted by foodborne Staphylococcus equorum WS2733, is biosynthesized nonribosomally. Eur J Biochem. 2001 Dec;268(24):6390-401. |