PeptideDB

MI 1544

CAS No.: 87565-51-3

MI 1544 is a LHRH antagonist.
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Description MI 1544 is a LHRH antagonist.
Synonyms Attcpl-LHRH, AttcplLHRH, MI-1544, MI1544, Attcpl LHRH
molecular weight 1429.09
Molecular formula C71H94ClN17O13
CAS 87565-51-3
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year
References 1. Vincze B, Pályi I, Daubner D, Kálnay A, Mezö G, Hudecz F, Szekerke M, Teplán I, Mezö I. Antitumour effect of a gonadotropin-releasing-hormone antagonist (MI-1544) and its conjugate on human breast cancer cells and their xenografts. J Cancer Res Clin Oncol. 1994;120(10):578-84. PubMed PMID: 7929528. 2. Mezö G, Mezö I, Pimm MV, Kajtár J, Seprödi J, Teplán I, Kovács M, Vincze B, Pályi I, Idei M, Szekerke M, Hudecz F. Synthesis, conformation, biodistribution, and hormone-related in vitro antitumor activity of a gonadotropin-releasing hormone antagonist-branched polypeptide conjugate. Bioconjug Chem. 1996 Nov-Dec;7(6):642-50. PubMed PMID: 8950483. 3. Kovács M, Koppán M, Mezö I, Teplán I, Flerkó B. Antiovulatory doses of antagonists of LH-RH inhibit LH and progesterone but not FSH and estradiol release. J Neuroendocrinol. 1993 Dec;5(6):603-8. PubMed PMID: 8680431. 4. Pályi I, Vincze B, Lovas S, Mezö I, Pató J, Kálnay A, Turi G, Gaál D, Mihalik R, Péter I, Teplán I, Murphy RF. Gonadotropin-releasing hormone analogue conjugates with strong selective antitumor activity. Proc Natl Acad Sci U S A. 1999 Mar 2;96(5):2361-6. PubMed PMID: 10051647; PubMed Central PMCID: PMC26789.