| Description | Methylprednisolone Aceponate (SH 440), a non-halogenated corticosteroid, is a potent anti-inflammatory agent. |
| Synonyms | MPA, SH 440, SH-440, SH440, Advantan, 醋丙甲泼尼龙 |
| molecular weight | 472.57 |
| Molecular formula | C27H36O7 |
| CAS | 86401-95-8 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 65 mg/ml (137.55 mM) |
| References | 1. Fölster-Holst R, Abeck D, Torrelo A. Topical hydrocortisone 17-butyrate 21-propionate in the treatment of inflammatory skin diseases: pharmacological data, clinical efficacy, safety and calculation of the therapeutic index. Pharmazie. 2016 Mar;71(3):115-21. Review. 2. Metz M, et al. Chronic pruritus associated with dermatologic disease in infancy and childhood: update from an interdisciplinary group of dermatologists and pediatricians. Pediatr Allergy Immunol. 2013 Sep;24(6):527-39. 3. García Ponte L, Ebert U. Frontiers of rapid itch relief: a review of methylprednisolone aceponate. J Eur Acad Dermatol Venereol. 2012 Nov;26 Suppl 6:9-13. 4. Blume-Peytavi U, Metz M. Atopic dermatitis in children: management of pruritus. J Eur Acad Dermatol Venereol. 2012 Nov;26 Suppl 6:2-8. |
| Citations | 1. Chen L, Zhao W, Li M, et al.SHP2 participates in decidualization by activating ERK to maintain normal nuclear localization of progesterone receptor.Reproduction.2023, 1(aop). |