| Description | Methyl reserpate (NSC 81464), a yohimbine-type alkaloid derived from the roots and leaves of Rauwolfia vomitoria, inhibits the transport of norepinephrine into chromophobe vesicles. |
| Synonyms | NSC81464, NSC 81464, NSC-81464, Me reserpate |
| molecular weight | 414.49 |
| Molecular formula | C23H30N2O5 |
| CAS | 2901-66-8 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Iwu M M, et al. Stem Bark Alkaloids of Rauwolfia vomitoria. Planta Medica, 1982, 45(2):105-111. 2. Mundorf ML, Troyer KP, Hochstetler SE, Near JA, Wightman RM. Vesicular Ca(2+) participates in the catalysis of exocytosis. J Biol Chem. 2000 Mar 31;275(13):9136-42. PubMed PMID: 10734047. 3. Parti R, Ozkan ED, Harnadek GJ, Njus D. Inhibition of norepinephrine transport and reserpine binding by reserpine derivatives. J Neurochem. 1987 Mar;48(3):949-53. PubMed PMID: 3806108. 4. GALA RR, REECE RP. Effect of a reserpine analogue, methyl-18-epi-o-methyl-reserpate hydrochloride, on lactogen release from rat anterior pituitary. Endocrinology. 1963 Apr;72:649-57. PubMed PMID: 13946186. |