| Description | Methyl 5-hydroxypyridine-2-carboxylate, a phenolic acid identified in the stems of Mahonia fortune, demonstrates in vitro inhibitory effects on nitric oxide (NO) production. |
| In vitro | Methyl 5-hydroxypyridine-2-carboxylate在LPS激活的RAW264.7和BV2细胞中抑制NO生成，其IC 50 分别为115.67和118.80 μM [1]。在6.25-200μM浓度范围内，Methyl 5-hydroxypyridine-2-carboxylate不表现出任何细胞毒性作用[1]。 |
| molecular weight | 153.14 |
| Molecular formula | C7H7NO3 |
| CAS | 30766-12-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 50 mg/mL (326.50 mM), Sonication is recommended. |
| References | 1. Liu L, et, al. Simultaneous characterisation of multiple Mahonia fortunei bioactive compounds in rat plasma by UPLC-MS/MS for application in pharmacokinetic studies and anti-inflammatory activity in vitro. J Pharm Biomed Anal. 2020 Feb 5;179:113013. |
Methyl 5-hydroxypyridine-2-carboxylate
CAS No.: 30766-12-2
Methyl 5-hydroxypyridine-2-carboxylate, a phenolic acid identified in the stems of Mahonia fortune, demonstrates in vitr
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