| Description | Methuosis inducer 1 is a potent methuosis inducer, with nticancer activity. |
| In vivo | Methuosis inducer 1 在MDA-MB-231细胞的异种移植小鼠模型中抑制肿瘤生长方面表现出显著的药理效果,且无明显副作用,使该化合物成为首个具有强大体内效力的Methuosis诱导剂。这些结果表明Methuosis诱导剂有可能作为治疗癌症的新型疗法。 |
| molecular weight | 487.48 |
| Molecular formula | C27H20F3N5O |
| CAS | 2240205-30-3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 22.5 mg/mL (46.16 mM) |
| References | 1. Wei H , Xihuan S , Yunzhan L , et al. Discovery and Identification of Small Molecules as Methuosis Inducers with In Vivo Antitumor Activities[J]. Journal of Medicinal Chemistry, 2018:acs.jmedchem.8b00753-. |