| Description | MeOIstPyrd is an anti-skin cancer agent that inhibits cell proliferation, migration, and spheroid formation through activation of the mitochondrial intrinsic apoptotic pathway. It induces DNA damage, activates p53, prolongs its half-life, and stabilizes p53 via ser15 phosphorylation. Additionally, MeOIstPyrd interfaces with MDM2 within the p53 sub-pocket, preventing the p53-MDM2 interaction [1]. |
| molecular weight | 304.37 |
| Molecular formula | C14H16N4O2S |
| CAS | 2308548-54-9 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |