| Description | Melanin Concentrating Hormone, salmon acetate (MCH (salmon)) is a 19 amino acid cyclic peptide, is largely expressed in the hypothalamus. |
| In vitro | 一种孤儿G蛋白偶联受体(SLC-1/GPR24)已被鉴定为MCH(MCHR1)的受体。MCHR2与MCHR1的蛋白质序列同源性高于任何其他G蛋白偶联受体。MCHR2特异性地被纳摩尔浓度的MCH激活，高亲和力结合MCH，并通过Gq蛋白发出信号[1]。 |
| In vivo | Melanin Concentrating Hormone集中激素刺激食欲。将Melanin Concentrating Hormone集中激素持续灌注至脑室系统可使食物摄入量在7-8天内增加[2]。Melanin Concentrating Hormone集中激素(10 μg/天)通过脑室内灌注后，可在常规饮食下使小鼠体重轻微但显著增加。长期刺激小鼠大脑中的Melanin Concentrating Hormone集中激素系统可能导致肥胖[3]。 |
| Synonyms | MCH (salmon), Melanin Concentrating Hormone, salmon acetate(87218-84-6 free base) |
| molecular weight | 2157 |
| Molecular formula | C91H143N27O26S4 |
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. An S, et al. Identification and characterization of a melanin-concentrating hormone receptor. Proc Natl Acad Sci U S A. 2001 Jun 19;98(13):7576-81. |
Melanin Concentrating Hormone, salmon acetate
CAS No.:
Melanin Concentrating Hormone, salmon acetate (MCH (salmon)) is a 19 amino acid cyclic peptide, is largely expressed in
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.