| Description | MDH1-IN-2 (7c) is a potent MDH1 inhibitor with an IC50 of 2.27 μM for MDH1 and 27.47 μM for MDH2. MDH1-IN-2 has potential anticancer activity and can be used in the study of diseases related to the immune system. |
| molecular weight | 427.53 |
| Molecular formula | C25H33NO5 |
| CAS | 2143463-35-6 |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 10 mg/mL (23.39 mM), Sonication is recommended. |
| References | 1. Naik R, et al. Methyl 3-(3-(4-(2,4,4-Trimethylpentan-2-yl)phenoxy)-propanamido)benzoate as a Novel and Dual Malate Dehydrogenase (MDH) 1/2 Inhibitor Targeting Cancer Metabolism. J Med Chem. 2017;60(20):8631-8646. |