| Description | Mca-RPPGFSAFK(Dnp)-OH, a fluorogenic substrate specifically designed for endothelin-converting enzyme-1 (ECE-1), enables the quantification of ECE-1 activity through its distinctive fluorescence signal. When ECE-1 cleaves this substrate, it releases 7-methoxycoumarin-4-acetyl (Mca), which exhibits excitation and emission maxima at 328 nm and 420 nm, respectively, allowing for the direct measurement of enzyme activity. |
| Synonyms | (7-methoxycoumarin-4-yl)acetyl-Arg-Pro-Pro-Gly-Phe-Ser-Ala-Phe-Lys(2,4-dinitrophenyl)-OH |
| molecular weight | 1388.44 |
| Molecular formula | C66H81N15O19.XCF3COOH |
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | 20% ACN/H2O: Soluble |