| Description | Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 (FS-6) is a quenched, fluorescent MMP peptide substrate designed for the real-time quantification of MMP enzymatic activity. As an extended variant of the MMP substrate (FS-1), it demonstrates increased specificity against collagenases (MMP-1, MMP-8, MMP-13) and MT1-MMP, evidenced by higher specificity constants (Ex/Em=325 nm/400 nm). [1] |
| In vitro | Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2的对胶原酶(MMP-1、MMP-8、MMP-13)以及MT1-MMP (MMP-14)的特异性常数(kcat/Km)较FS-1提高了2至9倍，相对增幅约为3倍[1]。 |
| Target activity | MMP1:27.5 μM (Km), MMP13:5.2 μM (Km), MMP14:7.9 μM (Km) |
| molecular weight | 1221.32 |
| Molecular formula | C55H80N16O16 |
| CAS | 720710-69-0 |
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2
CAS No.: 720710-69-0
Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 (FS-6) is a quenched, fluorescent MMP peptide substrate designed for the re
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