| Description | Mca-AVLQSGFR-K(Dnp)-K-NH2 serves as a fluorogenic substrate specifically designed for the main protease (Mpro) of the severe acute respiratory syndrome coronavirus (SARS-CoV), also referred to as 3C-like protease (3CLpro). This substrate, upon enzymatic cleavage by SARS-CoV Mpro, liberates 7-methoxycoumarin-4-acetyl (Mca) which emits fluorescence. This fluorescence emission, with excitation/emission peaks at 328/420 nm respectively, facilitates the quantification of SARS-CoV Mpro's catalytic activity. |
| molecular weight | 1514.70 |
| Molecular formula | C69H99N19O20.XCF3COOH |
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | 20% ACN/H2O: Soluble |