| Description | Mca-(Ala7,Lys(Dnp)9)-bradykinin is a fluorogenic substrate that demonstrates high sensitivity for ECE-1 (endothelin-converting enzyme-1). It features a (7-methoxycoumarin-4-yl)acetyl (Mca) group for fluorescence and a 2,4-dinitrophenyl (Dnp) group for quenching, yielding a significant increase in fluorescence when the substrate is cleaved [1]. |
| In vitro | Mca-(ala7,lys(dnp)9)-bradykinin 具有成为 neprilysin 的底物能力，但被 ECE-1 水解的效率高出10倍，因此这一底物对 ECE-1 具有选择性[1]。 |
| molecular weight | 1388.44 |
| Molecular formula | C66H81N15O19 |
| CAS | 323577-36-2 |
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
Mca-(ala7,lys(dnp)9)-bradykinin
CAS No.: 323577-36-2
Mca-(Ala7,Lys(Dnp)9)-bradykinin is a fluorogenic substrate that demonstrates high sensitivity for ECE-1 (endothelin-conv
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