| Description | MC2050 is a potent PARP-1 inhibitor. The IC50 for inhibition of PARP-1 activity is 119 nM, compared to 1.8 μM for PARP-2. MC2050 inhibits apoptosis and blocks poly ADP-ribosylation of histone H1 in hydrogen peroxide treated SH-SY5Y neuroblastoma cells. |
| molecular weight | 440.387 |
| Molecular formula | C19H23Cl2N5OS |
| CAS | 1301757-19-6 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |