| Description | MBRI-001 is a deuterium-substituted plinabulin derivative and a potent anti-cancer agent with better pharmacokinetic characteristics tand lower toxicity. |
| Synonyms | MBRI 001, MBRI001. BPI-2358-d, plinabulin-d, NPI-2358-d |
| molecular weight | 337.39 |
| Molecular formula | C19H20N4O2 |
| CAS | 2054938-28-0 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Ding Z, Cheng H, Wang S, Hou Y, Zhao J, Guan H, Li W. Development of MBRI-001, a deuterium-substituted plinabulin derivative as a potent anti-cancer agent. Bioorg Med Chem Lett. 2017 Mar 15;27(6):1416-1419. doi: 10.1016/j.bmcl.2017.01.096. PubMed PMID: 28228362. |