| Description | Matrixyl Acetate(214047-00-4 free base) (Palmitoyl pentapeptide) is a matrikine used in anti-wrinkle cosmetics. |
| Synonyms | Palmitoyl-KTTKS, Palmitoyl pentapeptide, Pal-Lys-Thr-Thr-Lys-Ser-OH, Matrixyl, 五胜肽 |
| molecular weight | 862.12 |
| Molecular formula | C41H79N7O12 |
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: Soluble |
| References | 1. Giangreco F, Höfinger S, Bakalis E, Zerbetto F. Impact of the green tea ingredient epigallocatechin gallate and a short pentapeptide (Ile-Ile-Ala-Glu-Lys) on the structural organization of mixed micelles and the related uptake of cholesterol. Biochim Biophys Acta Gen Subj. 2018 Sep;1862(9):1956-1963. doi: 10.1016/j.bbagen.2018.06.005. Epub 2018 Jun 15. PubMed PMID: 29886279. 2. Park H, An E, Cho Lee AR. Effect of Palmitoyl-Pentapeptide (Pal-KTTKS) on Wound Contractile Process in Relation with Connective Tissue Growth Factor and α-Smooth Muscle Actin Expression. Tissue Eng Regen Med. 2017 Jan 19;14(1):73-80. doi: 10.1007/s13770-016-0017-y. eCollection 2017 Feb. PubMed PMID: 30603464; PubMed Central PMCID: PMC6171572. 3. Choi YL, Park EJ, Kim E, Na DH, Shin YH. Dermal Stability and In Vitro Skin Permeation of Collagen Pentapeptides (KTTKS and palmitoyl-KTTKS). Biomol Ther (Seoul). 2014 Jul;22(4):321-7. doi: 10.4062/biomolther.2014.053. PubMed PMID: 25143811; PubMed Central PMCID: PMC4131521. 4. Rubinchik E, Schneider T, Elliott M, Scott WR, Pan J, Anklin C, Yang H, Dugourd D, Müller A, Gries K, Straus SK, Sahl HG, Hancock RE. Mechanism of action and limited cross-resistance of new lipopeptide MX-2401. Antimicrob Agents Chemother. 2011 Jun;55(6):2743-54. doi: 10.1128/AAC.00170-11. Epub 2011 Apr 4. PubMed PMID: 21464247; PubMed Central PMCID: PMC3101398. |