| Description | Marstacimab (PF-06741086), an anti-tissue factor pathway inhibitor (TFPI) monoclonal antibody, is utilized in hemophilia research [1] [2]. |
| In vitro | Marstacimab(20, 50 及 100 nmol/L)在血友病患者全血样本中降低了玉米胰蛋白酶(CT)[1]的活性。 |
| In vivo | Marstacimab(0.5 mg/kg;静脉注射)在小鼠急性出血模型中并不改变血流动态[2]。 |
| Synonyms | PF-06741086 |
| molecular weight | N/A |
| CAS | 1985638-39-8 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 years |