| Description | Maropitant is a selective neurokinin (NK1) receptor antagonist. |
| Synonyms | 马罗匹坦, 马罗皮坦 |
| molecular weight | 468.67 |
| Molecular formula | C32H40N2O |
| CAS | 147116-67-4 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 4.69 mg/mL (10 mM), Sonication is recommended. |
| References | 1. Hickman M A , Cox S R , Mahabir S , et al. Safety, pharmacokinetics and use of the novel NK‐1 receptor antagonist maropitant (Cerenia TM ) for the prevention of emesis and motion sickness in cats[J]. Journal of Veterinary Pharmacology and Therapeutics, 2008, 31(3):220-229. 2. Lesman S P , Boucher J F , Grover G S , et al. The pharmacokinetics of maropitant citrate dosed orally to dogs at 2 mg/kg and 8 mg/kg once daily for 14 days consecutive days[J]. Journal of Veterinary Pharmacology and Therapeutics, 2013, 36(5):462-470. 3. Williams-Fritze M J , Carlson Scholz J A , Zeiss C , et al. Maropitant Citrate for Treatment of Ulcerative Dermatitis in Mice with a C57BL/6 Background[J]. Journal of the American Association for Laboratory Animal Science, 2011. |