| Description | Mal-Pc, a phthalocyanine-based molecular photosensitizer featuring maleimides, interacts with GSH to diminish its levels and decrease aggregation, enhancing the ROS (Reactive Oxygen Species)-dependent efficacy of photodynamic therapy (PDT) in targeting cancer cells [1]. |
| In vitro | 具有两个顺式马来酰亚胺基团的Mal-Pc，在癌细胞中表现出更快的累积，并可与GSH发生反应，耗尽GSH并减少聚集，从而增强PDT的ROS介导抗癌效果[1]。荧光成像显示，由于反应产物的高亲水性，Mal-Pc能更快地从正常细胞中排除[1]。 |
| molecular weight | 876.86 |
| Molecular formula | C46H28N10O8Si |
| CAS | 2670367-74-3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |