| Description | Mal-NH-PEG6-CH2CH2COOPFP ester is a polyethylene glycol (PEG)-based linker known as a PROTAC linker, designed specifically for the synthesis of PROTACs[1]. |
| In vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| molecular weight | 670.58 |
| Molecular formula | C28H35F5N2O11 |
| CAS | 1599432-34-4 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. |
Mal-NH-PEG6-CH2CH2COOPFP ester
CAS No.: 1599432-34-4
Mal-NH-PEG6-CH2CH2COOPFP ester is a polyethylene glycol (PEG)-based linker known as a PROTAC linker, designed specifical
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