| Description | MAC173979 inhibits E. coli de novo PABA biosynthesis and growth. |
| Synonyms | MAC-173979, MAC 173979 |
| molecular weight | 246.05 |
| Molecular formula | C9H5Cl2NO3 |
| CAS | 41501-64-8 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Thiede JM, Kordus SL, Turman BJ, Buonomo JA, Aldrich CC, Minato Y, Baughn AD. Targeting intracellular p-aminobenzoic acid production potentiates the anti-tubercular action of antifolates. Sci Rep. 2016 Dec 1;6:38083. doi: 10.1038/srep38083. PubMed PMID: 27905500; PubMed Central PMCID: PMC5131483. 2. Zlitni S, Ferruccio LF, Brown ED. Metabolic suppression identifies new antibacterial inhibitors under nutrient limitation. Nat Chem Biol. 2013 Dec;9(12):796-804. doi: 10.1038/nchembio.1361. Epub 2013 Oct 13. PubMed PMID: 24121552; PubMed Central PMCID: PMC3970981. |