| Description | m-PEG4-azide, also referred to as 13-Azido-2,5,8,11-tetraoxatridecane, functions as a PEG-based PROTAC linker suitable for PROTACs synthesis[1]. |
| In vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| Synonyms | 13-Azido-2,5,8,11-tetraoxatridecane |
| molecular weight | 233.26 |
| Molecular formula | C9H19N3O4 |
| CAS | 606130-90-9 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| References | 1. Belen Begines, et al. Synthesis of Reduction Sensitive Comb-Like Polyurethanes Using Click Chemistry. Journal of Polymer Science Part A: Polymer Chemistry, 2016, 54(24), 3888-3900. |