| Description | LY2048978 is an effective and orally-bioavailable antagonist of kappa-selective. It has activity in animal models predictive of efficacy in mood and addictive disorders. |
| Synonyms | LY 2048978, LY-2048978 |
| molecular weight | 312.41 |
| Molecular formula | C19H24N2O2 |
| CAS | 676495-11-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Rorick-Kehn LM, Witkin JM, Statnick MA, Eberle EL, McKinzie JH, Kahl SD, Forster BM, Wong CJ, Li X, Crile RS, Shaw DB, Sahr AE, Adams BL, Quimby SJ, Diaz N, Jimenez A, Pedregal C, Mitch CH, Knopp KL, Anderson WH, Cramer JW, McKinzie DL. LY2456302 is a novel, potent, orally-bioavailable small molecule kappa-selective antagonist with activity in animal models predictive of efficacy in mood and addictive disorders. Neuropharmacology. 2014 Feb;77:131-44. doi: 10.1016/j.neuropharm.2013.09.021. Epub 2013 Sep 23. PubMed PMID: 24071566. |