| Description | LUF7346 is an allosteric modulator of hERG. |
| Synonyms | LUF-7346, LUF 7346 |
| molecular weight | 411.25 |
| Molecular formula | C20H15BrN2O3 |
| CAS | 1821638-40-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Sala L, Yu Z, Ward-van Oostwaard D, van Veldhoven JP, Moretti A, Laugwitz KL, Mummery CL, IJzerman AP, Bellin M. A new hERG allosteric modulator rescues genetic and drug-induced long-QT syndrome phenotypes in cardiomyocytes from isogenic pairs of patient induced pluripotent stem cells. EMBO Mol Med. 2016 Sep 1;8(9):1065-81. doi: 10.15252/emmm.201606260. Print 2016 Sep. PubMed PMID:27470144; PubMed Central PMCID: PMC5009811. |