| Description | LTB4-IN-1 (Anti-inflammatory agent 2) with IC50 of 70 nM is an inhibitor of leukotriene synthesis (LTB4). |
| In vitro | Leukotriene acts as a mediator for various inflammatory and allergic conditions due to its various pro-inflammatory properties. |
| Target activity | LTB4:70 nM |
| Synonyms | Anti-inflammatory agent 2 |
| molecular weight | 466.59 |
| Molecular formula | C26H30N2O4S |
| CAS | 133012-00-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 50 mg/mL (107.16 mM) |
| References | 1. Hatzelmann A, et al. Inversely-correlated inhibition of human 5-lipoxygenase activity by BAY X1005 and other quinoline derivatives in intact cells and a cell-free system--implications for the function of 5-lipoxygenase activating protein. Biochem Pharmacol. 1994 Jun 15;47(12):2259-68. |