| Description | LT-540-717 (compound 32), a potent FLT3 inhibitor (IC50=0.62 nM), exhibits antiproliferative activity and effectively inhibits various acquired FLT3 mutations, including FLT3 (ITD, D835V), FLT3 (ITD, F691L), FLT3 (D835Y), and FLT3 (D835V), indicating its potential as an anti-AML agent [1]. |
| molecular weight | 456.5 |
| Molecular formula | C24H24N8O2 |
| CAS | 2143089-35-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |