| Description | LSP-249 is a plasma kallikrein inhibitor under the study for angioedema, with an EC50 less than 100 nM in cell. |
| Target activity | Kallikrein:< 100 nM (EC50) |
| molecular weight | 431.92 |
| Molecular formula | C24H22ClN5O |
| CAS | 1801253-04-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 31.25 mg/mL (69.45 mM), Sonication and heating to 60℃ are recommended. |
| References | 1. Andrew Mcdonald, et al. Therapeutic inhibitory compounds. Patent. WO2016011209A1. |