| Description | LRH-1 Inhibitor-3 is the first small molecule LRH-1 activity antagonist. |
| Synonyms | LRH1 Inhibitor 3, LRH-1-Inhibitor-3 |
| molecular weight | 375.46 |
| Molecular formula | C23H25N3O2 |
| CAS | 1185410-60-9 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Jiang Y, Zhao Y, Chen S, Chen L, Li C, Zhou X. Regulation by FSH of the dynamic expression of retinol-binding protein 4 in the mouse ovary. Reprod Biol Endocrinol. 2018 Mar 20;16(1):25. doi: 10.1186/s12958-018-0348-8. PubMed PMID: 29558965; PubMed Central PMCID: PMC5859637. 2. Salmenkari H, Holappa M, Forsgard RA, Korpela R, Vapaatalo H. Orally administered angiotensin-converting enzyme-inhibitors captopril and isoleucine-proline-proline have distinct effects on local renin-angiotensin system and corticosterone synthesis in dextran sulfate sodium-induced colitis in mice. J Physiol Pharmacol. 2017 Jun;68(3):355-362. PubMed PMID: 28820392. 3. Yang FM, Feng SJ, Lai TC, Hu MC. A calreticulin-dependent nuclear export signal is involved in the regulation of liver receptor homologue-1 protein folding. Biochem J. 2015 Oct 15;471(2):199-209. doi: 10.1042/BJ20150252. Epub 2015 Aug 12. PubMed PMID: 26268559. 4. Bianco S, Jangal M, Garneau D, Gévry N. LRH-1 controls proliferation in breast tumor cells by regulating CDKN1A gene expression. Oncogene. 2015 Aug 20;34(34):4509-18. doi: 10.1038/onc.2014.382. Epub 2014 Dec 1. PubMed PMID: 25435372. |