| Description | Lorundrostat (MT-4129) is an aldosterone synthase inhibitor with antihypertensive activity that lowers systolic blood pressure. |
| Synonyms | MLS101, MT 4129, MLS-101, MT4129, MT-4129, MLS 101 |
| molecular weight | 451.56 |
| Molecular formula | C24H33N7O2 |
| CAS | 1820940-17-7 |
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 20 mg/mL (44.29 mM), Sonication is recommended. |
| References | 1. Laffin LJ, et al. Aldosterone Synthase Inhibition With Lorundrostat for Uncontrolled Hypertension: The Target-HTN Randomized Clinical Trial. JAMA. 2023 Sep 26;330(12):1140-1150 |