| Description | Lophine (NSC-62790) can be used in the synthesis of protein kinase inhibitors, calcium antagonists, strong Chemicalbook cardiac agents, and antitumor drugs. Lophine derivatives act as in vitro chemiluminescent activators for the detection of free radicals. |
| Synonyms | 2,4,5-Triphenylimidazole, 2，4，5-三苯基咪唑, NSC 62790, NSC-62790, NSC62790 |
| molecular weight | 296.37 |
| Molecular formula | C21H16N2 |
| CAS | 484-47-9 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 11 mg/mL (37.12 mM) |
| References | 1. Honda S, Toyota T. Photo-triggered solvent-free metamorphosis of polymeric materials. Nat Commun. 2017 Sep 11;8(1):502. 2. Pavlova E, et al. Synthesis and physicochemical properties of novel lophine derivatives as chemiluminescent in vitro activators for detection of free radicals. Eur Biophys J. 2015 Dec;44(8):623-34. 3. Zheng W, et al. Colorimetric fluorescent cyanide chemodosimeter based on triphenylimidazole derivative. Spectrochim Acta A Mol Biomol Spectrosc. 2014 Apr 24;124:97-101. 4. Kishikawa N, et al. A novel lophine-based fluorescence probe and its binding to human serum albumin. Anal Chim Acta. 2013 May 30;780:1-6. |