Description | Liquidambaric lactone is a compound isolated from Euonymus grandiflorus Wall.Liquidambaric lactone may have inhibitory HIV-1 reverse transcriptase activity. |
In vitro | 在从千屿梨(Lantana camara L.)根部酒精提取物通过硅胶柱色谱得到的25个馏分中,有三个馏分显示出抑制HIV-1逆转录酶的活性。进一步通过减压柱色谱分离出六种五环三萜类化合物,并通过光谱分析鉴定为:豆甾酸(1)、Liquidambaric lactone(2)、lantadene A(3)、lantadene B(4)、齐墩果酸(5)以及25-羟基齐墩果酸(6)。其中,化合物2和6为首次在马鞭草科(Verbenaceae)植物中报道,且6的结构通过X射线晶体学首次确认。 |
molecular weight | 468.67 |
Molecular formula | C30H44O4 |
CAS | 185051-75-6 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
References | 1. Roots of Lantana camara:Chemical Constituents and HIV-1 Reverse Transcriptase Inhibitory Activity. Natural Product Research & Development, 2011 , 23 (1) :25-29. |